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They then compared the two groups to see whether they had been newly prescribed high-dose or low-dose statins. The researchers say there is already some evidence that statin use could lead to kidney problems and that there may be a potential dose response, but uncertainty what is considered a low dose of atorvastatin the association remains.fatal CHD or nonfatal MI by 36% and the risk of undergoing revascularization procedures by 42% Lipoprotein concentrations were lowered to levels similar to those observed with atorvastatin 10 mg daily in previous clinical studies.

The risk of fatal and nonfatal stroke was reduced by 26% although this was not statistically significant.

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The estimated background risk of major birth defects and miscarriage for the indicated population is unknown.If symptoms resolve and CK levels return to normal, then re-introduction ofatorvastatin or introduction of an alternative statin may be considered at thelowest dose and with close monitoring. Atorvastatin must be discontinued if clinically significant elevation of CKlevels 10 x ULN occur, or if rhabdomyolysis is diagnosed or suspected.

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5 for atorvastatin versus. 8 in the subgroup of patients with prior haemorrhagic stroke.ultum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

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Mmol/L during treatment with atorvastatin and 129 mg/dL 3. mmol/L during atorvastatin low dose with placebo.In the present study, we examined the atorvastatin low doses of statins on cytokine production from lipopolysaccharide LPS stimulated human bronchial epithelial cells BEAS-2B Interleukin IL 6 and IL-8 mRNA expression and protein secretion in LPS-stimulated cells were inhibited significantly by the lipophilic statin pitavastatin and the hydrophilic statin pravastatin.

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