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It should not be used in pregnant women unless, in the judgment of the physician, it is essential for the welfare of the patient.Since both oral retinoids, including isotretinoin and acitretin, and the tetracyclines, primarily minocycline, can what are doxycycline hyclate pills for increased intracranial pressure, the concurrent use of an oral retinoid and a tetracycline should be avoided.

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