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Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.Parenteral dihydroergotamine or 5-HT1 selective receptor agonists are particularly useful in patients with rapid onset of migraine, and parenteral and intranasal preparations of these drugs may be particularly useful in those unable to take oral drugs because of severe nausea and/or vomiting.

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No fetal effects were observed in rats receiving 50 mg/kg daily representing 5 times the maximum single sumatriptan succ 50mg human dose of 100 mg on a mg/m basis Sumatriptan has been shown to be teratogenic in pregnant rats given long-term oral sumatriptan dosages of 500 mg/kg daily representing 50 times the maximum single human oral dose of 100 mg on a mg/m basis an increased incidence of a syndrome of malformations short tail/short body and vertebral disorganization sumatriptan succ 50mg observed in these animals.You should take your treatment as soon as possible at the onset of migraine symptoms.

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