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Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.Parenteral dihydroergotamine or 5-HT1 selective receptor agonists are particularly useful in patients with rapid onset of migraine, and parenteral and intranasal preparations of these drugs may be particularly useful in those unable to take oral drugs because of severe nausea and/or vomiting.

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Especially for chronic migraine sufferers, sumatriptan offers great pain relief. It can also be taken as a sumatriptan nasal spray if severe nausea makes swallowing tablets impractical.Apply the patch to clean, dry, and hairless skin on your thigh or the outer part of your upper arm.

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