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Cutaneous hypersensitivity reactions including, among others, skin rashes and angioedema. Very rare cases of serious skin reactions have been reported.Initial plasma concentrations above 150 mcg per mL 993 micromoles/L at 4 hours, 100 mcg per mL 662 micromoles/L at 6 hours, 70 mcg per mL 463.

micromoles/L at 8 hours, 50 mcg per mL 331 micromoles/L at 10 hours, 20 mcg per mL 132.

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Persistent sore throat or fever easy bruising/bleeding."Acetaminophen: Avoiding Liver Injury". U. Food and Drug Administration FDA 24 June 2009.

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