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Clinical data
Pronunciation/ r oʊ ˈ s uː v ə s t æ t ɪ n / roh- SOO -və-stat-in
Trade namesCrestor, Rosulip, Zuvamor, others
Pregnancy categoryAU: D US: X (Contraindicated)
Routes of administrationBy mouth (tablets)
ATC codeC10AA07 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability20% [1]
Protein binding88% [1]
MetabolismLiver: CYP2C9 (major) and CYP2C19-mediated; ~10% metabolized [1]
MetabolitesN -desmethyl rosuvastatin (major; 1/6–1/9 of rosuvastatin activity) [2]
Elimination half-life19 hours [1]
ExcretionFaeces (90%) [1]

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