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Metoprolol
Clinical data
Pronunciation/ m ɛ ˈ t oʊ p r oʊ l ɑː l /, / m ɛ t oʊ ˈ p r oʊ l ɑː l /
Trade namesLopressor, Metolar XR, others
AHFS/Drugs.comMonograph
MedlinePlusa682864
License dataUS   FDA: Metoprolol
Pregnancy categoryAU: C US: C (Risk not ruled out)
Routes of administrationBy mouth, IV
Drug classBeta blocker
ATC codeC07AB02 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability50% (single dose) [1] 70% (repeated administration) [2]
Protein binding12%
MetabolismLiver via CYP2D6, CYP3A4
Elimination half-life3–7 hours
ExcretionKidney

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Toprol information
Pill name Toprol
Active substancesmetoprolol
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    A healthcare provider will give you this injection in a medical setting where your heart and blood pressure can be monitored.In this case, just leave out the missed dose and take your next dose as normal. Never take 2 doses at the same time.

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    For Toprol-XL, the percent reduction in exercise heart rate was relatively stable throughout the entire dosage interval and the level of beta1-blockade increased with increasing doses from 50 to 300 mg daily.

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    There is very limited experience with the use of hemodialysis to remove metoprolol, however metoprolol is not highly protein bound.A Toprol XL tablet can be divided in half if your doctor has told you to do so. Swallow the half-tablet whole, without chewing or crushing.

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    No what doe toprol treat of impaired fertility due to metoprolol tartrate was observed in a study performed in rats at doses up to 22 times, on a mg/m2 what doe toprol treat, the daily dose of 200 mg in a 60-kg patient.It is not known whether metoprolol will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia dangerously high blood pressure that can lead to medical problems in both mother and baby The benefit of treating hypertension may outweigh any risks to the baby.

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